National anti-hepatitis drug - five Liuwei Tablets

"Five Liuwei Tablets" by the National Drug Certificate

By the State Food and Drug Administration approval, the hospital's development, "Wu Ling Liu Wei Di film" National Drug Certificate (card Res word Z20060246).

"Liu Wei Wu Ling-chip" is the hospital three generations of experts, after 39 years with great concentration to develop the country's three categories of Chinese medicine, anti-hepatitis drug JiangMei. In 1967 in our hospital team leader Professor Chen Jumei at home for the first time found that Schisandra Jiang Mei, was found to become the first person to JiangMei medicine, Chinese medicine treatment in China filled a gap in the field of liver disease, medicine can not be broken down for a long time Enzyme international point of view. And in the clinical application of Schizandrin agents, "a liver Ning," Jiang Mei made sure that effect, Chinese medicine in the treatment of chronic severe hepatitis on the problem was a major breakthrough.

In 1983, "a liver Ning" on the basis of the party group, made of non-standard agents in our hospital, "a liver Ning, Ⅱ pill" for clinical treatment of chronic viral hepatitis, after years of clinical observations, confirmed that a significant effect , The majority of doctors and patients have been warmly welcomed by the masses, has made a good social benefits.

In 1999, the hospital group using the traditional Chinese medicine theory and cutting-edge technology ultrafine Modernization of Traditional Chinese Medicine, from the experimental animals, cells, molecular and clinical aspects, and so on, a systematic and standard in-depth study by the national 7 Hospitals were well-known multi-center, randomized, double-blind and multi-center, randomized, open method of DDB and control, carried out Ⅱ, Ⅲ clinical trials. The clinical trial lasted 21 months, a total of 661 cases of patients into the group, of which, Ⅲ period of the test group, the control group were 324 cases, 108 cases. Clinical trial data and found that five Liuwei Tablets is safe and highly effective drug in the treatment of chronic hepatitis B has a significant role in Jiang Mei, and the effect of the treatment of JiangMei more lasting stability.

April 6, 2006, "a liver Ning" State Food and Drug Administration approved three new drugs for the country, changed its name to "Liuwei five Tablets." August 1, 2006 officially listed on the product, a product on the market for its stability, the exact effect, won the majority of the patients recognized at the same time attracted a large number of domestic pharmaceutical agents of great concern, calls have come to discuss cooperation matters agent; They said the market is weeding liver medicine, to choose a good drug will not only bring enormous wealth and, more importantly, for the majority of patients with liver disease brought about by the gospel and living a healthy confidence.

January 31, 2007, Liu Wei won the third of five Tablets (2006) "Chinese medicine market of the 10 types of liver influential brand" title, which not only proves that the majority of consumers, "Liu Wei Wu Ling-chip" definitely And trust, as well as more established five Liuwei Tablets in the industry leading brand.

Link: The central government portal website (Source: Guangming Daily on July 12, 2006) http://www.gov.cn/fwxx/jk/2006-07/12/content_333418.htm

Liu Wei-ling five films, "two, three, five,"

Difference between the two:

Liu Wei-ling five films come out, and fully reflects the different disease Tongzhi, a two-drug use, Kidney Liver take the theory of Chinese medicine

Exclusive patent production

Three major characteristics:

Efficient: After eight joint authority to verify, hundreds of thousands of clinical observation, JiangMei efficient as high as 92.49 percent, the total effective 90%.

Safety: After hundreds of thousands of clinical applications, non-toxic side effects reaction.

Low rebound: a stable and lasting effect, stopping in a timely manner, by the emergence of the virus to reproduce and the resulting rebound is low.

Five features:

★ JiangMei liver, liver cells to repair: five Liuwei Tablets are rich in trace elements of the effective removal of liver cells caused by oxidative damage and peroxidase activity of free radicals to prevent liver cell damage. At the same time, five Liuwei Tablets containing a variety of biological factors, under certain conditions, into a blood vessel repair GRT factor, not only to repair damaged liver cells, but also have to make regeneration.

★ anti-fibrosis, cirrhosis block: Liu Wei-ling five films through a variety of mechanisms hepatic cells increased synthesis of apolipoprotein. Apo will be out of triglycerides and fatty liver. Tablets Liuwei five large number of components of biological inhibited fat liver caused by transforming growth factor TGF-β release, the avoidance of hepatic stellate cell activity in order to prevent liver fibrosis and cirrhosis.

★ immune regulation, immune function reconstruction: Liu Wei-ling five films with two-way regulating immune function in different states have different immune regulatory role, cyclophosphamide can reduce the 1L-2 increased, so that the cause azathioprine The 1L-2 inhibition by the extraordinary rise in the face of no significant impact on the normal group, showing a clear two-way adjustment.

★ inhibit viral replication: Liuwei five Tablets of duck hepatitis B virus infection in the treatment of animal tests confirmed that the five Liuwei Tablets more significant role in anti-hepatitis B virus, and to prove induced endogenous interferon-related. Through a specific mechanism to activate the liver cells of the antiviral protein gene to produce anti-viral protein, the virus has cut off the messenger RNA (mRNA), inhibition of virus replication, inhibition of the virus in the liver cell penetration, and shell assembly, In order to achieve the kill, suppress the virus.

★ liver tissue to prevent the emergence of new bio: Liuwei five Tablets after clinical verification, the active ingredient can suppress tumor necrosis factor TNF-α release of the complex, inhibiting tumor cell proliferation and tumor cell current regulation can undermine the growth of cancer cells, Cancer cells to apoptosis, cancer cells block the recurrence of cancer cells to prevent the spread of the transfer and ease the pain of cancer.

Prescription data

Drug name】 【Liuwei five Tablets

Hanyu Pinyin: liuweiwulingPian

Ben Pinwei Baomoyipian】 【traits, except for the clothes after the film significantly tan; micro-gas smell and taste Wei Ku.

【】 Country, the text approved by Yao Zhunzi Z20060238

】 【Pharmacological effects of animal test results suggest that: Ben Pinke inhibit CCl4 caused the elevated serum aminotransferase, total protein (TP) and albumin (ALB) lower, reducing the liver collagen content; inhibiting D-galactosamine (D-GalN) due to increased serum aminotransferase. On the BCG (BCG) plus lipopolysaccharide (LPS)-induced liver injury in mice immune protective effect; half of the mice to promote hemolysin reticuloendothelial system and the phagocytosis, to increase the rate of lymphocyte transformation. Of paracetamol-induced liver injury in mice alkaline (ALP) activity decreased significantly, blood triglyceride (TG) decreased; so that the methyl bromide sodium phthalate (BSP) in the mouse liver retention capacity has decreased role . 2.2.15 inhibit cell surface antigen (HBsAg), e antigen (HBeAg) replication and expression; suppression of hepatitis B virus infection in the duck-duck-duck serum HBV DNA increase.

【】 Kidney Liver function attending, activating blood detoxification. For the treatment of chronic hepatitis B increased aminotransferase, TCM liver and kidney belong to the lack of hot blood Xiedu each node, Zheng Jian: Xie Lei pain, fatigued Yao Xi, Yan Zao dry mouth, fatigue, weakness, Nacha, Expansion Wan, who heads yellow or yellow, the color yellow urine, dizziness dazzling, the two heads of dry, hot hand, foot and mind, insomnia and more dreams, An Hong tongue or petechiae, less moss or moss, small pulse string.

】 【Use of oral dosage, a 3, the 3rd day, and even served for 3 months; then monthly decline, and even served for 3 months. The first reduction in January, a 3 day 2; the first reduction in February, a 2, 2nd day; the first reduction in March, a 2 day 1st.

】 【Side effects in clinical trials, 1 case of patients with abnormal electrocardiogram (left branch block, T-wave changes), and test whether the drugs can not be identified.

】 【Taboo banned pregnant women.

Notes】 【avoid alcohol and spicy food stimulation.

】 【Specifications each weight 0.5g (Baomoyipian).

Key Storage】 sealed.

【】 Pharmaceutical packaging plastic bottle packaging, bottle 60; pharmaceutical plastic bottle packaging, bottle 100; medicinal aluminum double-blister packaging, 12 per plate, the plate pack 3; medicinal aluminum double-blister packaging , 15 per plate, the plate 4 per box.